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Multiple System Atrophy: A case study in hope for rare diseases
By Jan Shultis During the last few weeks of 2025, Houston-area clinical research organization Hope Biosciences Research Foundation (HBRF) received Food and Drug Administration (FDA) authorization to administer Hope Biosciences’ allogeneic (donor) adipose-derived mesenchymal (adult) stem cells (HB-adMSCs) to seven men and women living with Multiple System Atrophy (MSA). As HBRF shared in their announcement, the occasion is noteworthy both for authorization of research in a rar
Jan Shultis, Ph.D.
Mar 284 min read


Hope Biosciences Deploying New Cellular Therapeutic for Acute Kidney Injury
FOR IMMEDIATE RELEASE By Jan Shultis Sugar Land, Texas, 3 February 2026 - A multicenter trial stretching across the southwestern United States is now recruiting patients to investigate whether allogeneic (donor-derived) Hope Biosciences Adipose-derived Mesenchymal Stem Cells (HB-adMSCs) can prevent progression of trauma-induced Acute Kidney Injury (AKI), an abrupt decline in renal function that occurs over hours to days in up to 50% of trauma and burn patients and has few eff
Jan Shultis, Ph.D.
Feb 33 min read


2025 Annual Review
Happy, happy 2026, Hope community! One of our favorite parts of welcoming a new year is to reflect on the period concluding. There are many ways to present annual reviews, and in the near-decade since our founding we have tried many, from formal materials and presentations to stakeholder reports. This year, however, we’re trying something new – we want to celebrate the year with those who made it possible, in plain language. We want to celebrate with you. If you prefer to
Jan Shultis, Ph.D.
Jan 94 min read
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